- S W
Sam WorthingtonJake Sully
- Z S
Zoe SaldañaNeytiri
- S W
Sigourney WeaverKiri
- S L
Stephen LangColonel Miles Quaritch
- K W
Kate WinsletRonal
- C C
Cliff CurtisTonowari
- J D
Joel David MooreNorm Spellman
- C P
CCH PounderMo'at
- E F
Edie FalcoGeneral Frances Ardmore
- J C
Jemaine ClementDr. Ian Garvin
- G R
Giovanni RibisiParker Selfridge
- B D
Britain DaltonLo'ak
- J F
Jamie FlattersNeteyam
- T J
Trinity Jo-Li BlissTuktirey 'Tuk'
- J C
Jack ChampionMiles 'Spider' Socorro
- B C
Brendan CowellMick Scoresby
- B B
Bailey BassTsireya
- F G
Filip GeljoAonung
- D E
Duane Evans Jr.Rotxo
- D R
Dileep RaoDr. Max Patel
- M G
Matt GeraldRecom Wainfleet
- R O
Robert OkumuTa'unui Olecthan
- J S
Jennifer StaffordTa'unui Tsahik / Troupe
- K J
Keston JohnTarsem
- K D
Kevin DormanRecom Mansk / Troupe
- A V
Alicia Vela-BaileyRecom Zdinarsik / Troupe
- S A
Sean Anthony MoranRecom Fike
- A A
Andrew ArrabitoRecom Prager
- J A
Johnny AlexanderRecom Ja / Troupe
- K D
Kim DoRecom Zhang
- V T
Victor T. LopezRecom Lopez
- M W
Maria WalkerRecom Walker
- P B
Phil BrownStringer
- J C
Jocelyn ChristianBio Lab Tech
- J T
Joel TobeckNeuroscientist
- M E
Moana EteFemale Med-Tech
- P P
Phil PeletonMale Med-Tech
- J L
Jamie LandauMetkayina Warrior / Troupe
- J M
Jim MooreMako Sub #1 Pilot
- B H
Benjamin HoetjesMako Sub #1 Gunner
- N T
Nikita Tu BryantMako Sub #2 Pilot
- A A
Anthony AhernMako Sub #2 Gunner
- S R
Shane RangiMatador Co-Pilot
- R L
Rick LucasKestrel Pilot
- T D
Tanya DreweryNeurotech #1
- A D
Ava DiakhabyNeurotech #2
- I T
Isaac Te ReinaSea Dragon First Mate
- E F
Eric FarmerCrabsuit Pilot
- P M
Philip MtamboSkel Trooper
- D L
Daniel LoughSpider Double
- C M
Cruz MoirYoung Spider
- A L
Alex LucasToddler Spider
- S F
Scarlett FernandezYoung Kiri
- C C
Chloe ColemanYoung Lo'ak
- J I
Jeremy IrwinYoung Neteyam
- K B
Kacie BorrowmanTroupe
- C R
Courtney RosemontTroupe
- J R
Julene ReneeTroupe
- J M
Jake McLeanTroupe
- K H
Kevin HendersonTroupe
- S D
Shawn DriscollTroupe
- D C
Devereau ChumrauTroupe
- T K
Tarikura KapeaTroupe
- C J
CJ JonesMetkayina Interpreter (uncredited)
